Yes, A .223 Wylde chamber is a hybrid rifle chamber designed to allow .223 caliber barrels to safely fire both .223 Remington and 5.56×45mm NATO ammunition.
223 Wylde is a hybrid rifle chamber that allows you to shoot both .223 and 5.56×45 ammo from the firearm safely. Technically speaking, a 223 Wylde rifle has identical chamber angling as a 5.56×45 rifle but also brings a .2240 freebore diameter. Freebore is the space between a rifle’s chamber and the rifling in the barrel. Tighter freebore size in a 223 Wylde rifle allows you to shoot .223 ammo with better accuracy from it than a 5.56×45 rifle.
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Yes, you can safely shoot 5.56 NATO ammunition in a .223 Wylde chambered rifle without any issues or concerns. The .223 Wylde chamber is designed to offer the best performance for both .223 Remington and 5.56 NATO ammunition.