The pistol has multiple safety features. I have this pistol. Please check the user Manuel if you don’t understand.

Terry, There are a lot of safety features on the HP22. Make sure the safety and magazine safety are in fire position. I have 2 that function well. It is a rim fire pistol. Can contact PA in CA. Phone 909.937.6900 Fax: 909.937.0060

Assuming you have loaded everything correctly, you probably need to contact the manufacturer. These little 22s often require 'follow up' attention to properly function.