Sean, is would personally go with the sig p365. I'm a big boy so I went with the p365 xl and fantastic pistol. I've shot my friends 43x and while both great pistols but prefer the 365. Honestly both are great and I'm sure you will be happy with either. Just depends mostly on Wich one you like better. Hope this helps and good luck with your choice.

I go glock 43x all the way, but having the p365, it's a good fit, mag capacity is 10 plus 1 and second mag it comes with is 12 plus 1, for single stacked pistols it already is superior as to where the glock 43x will hold 10 plus 1 but is double stacked. It's small, great grip, sights, and for conceal carry its a go to. Look into how it feels in your hand, test shoot it at ranges if you have access and that will most likely determine which one you will get. I lean more towards the p365 just because I shot them and it's just a good fit for me.

Honestly it's up to your personal preference. Go to a store and pick each one up. See how each one feels in your hand. The G43x feels better in my hand as the handle is longer without the need of an extended mag. You can also get an aftermarket mag that will hold 15 rounds. I would go with a G43x, but what works for me might not work for you. Hope this helps.

Sean, I have a Ruger EC9s and a Sig P365. I had a similar dilemma and chose the P365 and could not be happier with it although I own several Glocks as well. It is ergonomically superior to the G43x all things considered. Cheers and stay safe!

Sean, comparison here >>> https://gunmagwarehouse.com/blog/sig-p365-vs-glock-43x-battle-of-the-latest-ccws/