Hi Scott and welcome to the community. The Ruger American Compact does not have the magazine disconnect. The SR9 model does. Some good details here : gunsholstersandgear.com/gun-reviews/ruger-american-compact-pistol-review/#:~:text=Unlike%20some%20guns%20with%20a,people%20of%20all%20hand%20persuasions.

There is no magazine disconnect with this model. Once the magazine is removed it can still fire a chambered round.

Good morning Scott. No sir, this gun does not have a magazine disconnect. It will fire with the magazine removed.
Stay safe & have a great day!